The GAB2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GAB2. This antibody recognizes Human antigen. The GAB2 Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Immunohistochemistry.
Description
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis